Estimating the Level of Interleukin-22 in Sera of Patients with Uropathogenic Escherichia coli Infection in Mosul City

Background: Urinary tract infections (UTIs) were infectious diseases of the urinary system, that caused by different causative agents, including fungi, parasites, viruses, and bacteria. The current study was designed to isolate bacteria from UTI choose E. coli isolates levels interleukin-22 in patients infected with it. Furthermore, studying prevalence type 1 fimbriae (fimH) virulence gene isolated above patients. Methods: In present study, a total (140) midstream urine serum samples collected (110 females 30 males) age ranged between 10 65 years, who had signs symptoms primarily diagnosed physician Al-Salam Teaching Hospital – Mosul/Iraq during period January March 2021, while thirty-four healthy individuals studied as controls for ELISA test. Identification bacterial done microscopical examination, biochemical tests, (API 20E). disc diffusion method used antibiotic sensitivity test, DNA extracted detection. addition, level determined via technique. Results: mean ± SD (32.95 12.80) group (35.55 13.51) years. Additionally, most common patient frequency percentage 50 (35.7%). when compared control group, IL- 22 significantly higher patient's due infection (P<0.001). Moreover, fimH 47 (94.0%) positive gene. Conclusion: revealed infection, highest Meropenem, Nitrofurantoin (F15) Chloramphenicol also UTIs group. Therefore, IL-22 could be biomarker UTI. isolates.